VIDYASAGAR UNIVERSITY Faculty Information System

Self Declared Document

Name Dr. Anirban Basu Designation Assistant Professor Department Name CHEMISTRY Office Phone No +91 3222 298-376 / Centrex Extn. 376 Email ID anirbanbasu@mail.vidyasagar.ac.in Fax - Mobile No 9836464625 Personal Website Address Department of Chemistry and Chemical Technology Vidyasagar University Midnapore 721102 West Bengal

Educational Qualification Degree Name Institute Year of passing/awarded Post-Doctoral Experience Jadavpur University 2018 Post-Doctoral Research Associate CSIR-Indian Institute of Chemical Biology 2016 Ph.D. CSIR-Indian Institute of Chemical Biology (Degree awarded by Jadavpur University) 2013 Title of the Ph. D. Thesis “Synthesis of substituted derivatives of plant alkaloid berberine and studies on their DNA and RNA binding aspects”.

Career Profile / Teaching Experience Assistant Professor in the Department of Chemistry and Chemical Technology at Vidyasagar University from 8th August, 2018. Guest Lecturer at Jogesh Chandra Chaudhuri College (affiliated to University of Calcutta) in the Department of Chemistry for the academic session 2017-2018.

Specialization/Research Area Field of Specialization Research Area/ Areas of Interest Organic Chemistry & Biophysical Chemistry Synthesis of analogs of medicinally important alkaloids with better therapeutic potential. Interaction of Drugs with DNA and RNA: Molecular basis of the antitumor and anticancer action of alkaloids through biophysical studies. Binding of a number of medicinally important natural products and small molecules to polymorphic nucleic acid structures like duplex, triplex and quadruplexes. Micro RNA-mRNA interaction. DNA and RNA polymorphism. Photochemistry and photobiology of alkaloids. Protein-protein and protein-nucleic acid interactions. Protein-ligand interaction. Protein folding and aggregation. Synthesis and characterization of nanoconjugates of therapeutically important small molecules and studies on their interaction with nucleic acids and transport proteins.

Course/ Subject Taught Organometallic Chemistry Photochemistry Heterocyclic Chemistry Alkaloids Biologically Active Molecules

Conference/ Symposium /Journal Paper / Books Published International Publication Title Published in Year Published by Interaction of proflavine with the RNA polynucleotide polyriboadenylic acid-polyribouridylic acid: Photophysical and calorimetric studies. J. Biomol. Struct. Dyn. 38, 1590-1597. 2020 Taylor & Francis Interaction of the putative anticanceralkaloid chelerythrine with nucleic acids:biophysical perspectives Biophys. Rev. 12, 1369-1386. 2020 Springer Effect of crown ether, 15-crown-5, on lysozyme amyloid fibrillation. J. Biomol. Struct. Dyn., 37 (Supplement), 7. 2019 Taylor & Francis A calorimetric characterization of the interaction of quinacrine with poly(I).poly(C) and its comparison to proflavine J. Chem. Thermodyn. 131, 592-598. 2019 ELSEVIER Antiamyloid activity of functionalized cerium oxide nanoparticle on lysozyme fibrillation: Spectroscopic and microscopic investigation Materialia, 6, 100285. 2019 Elsevier Influence of the ionic liquid 1-butyl-3-methylimidazolium bromide on amyloid fibrillogenesis in lysozyme: Evidence from photophysical and imaging studies. Int. J. Biol. Macromol. 107, 2643-2649. 2018 ELSEVIER Thermodynamic investigation of Hoechst 33258-poly(A).poly(U) binding through calorimetric studies. J. Chem. Thermodyn. 126, 91-96. 2018 ELSEVIER Nucleic acids binding strategies of small molecules: Lessons from alkaloids. Biochim. Biophys. Acta 1862, 1995-2016. 2018 ELSEVIER Thermodynamic analysis of the complexation of quinacrine with tRNAPhe. J. Chem. Thermodyn. 120, 27-32. 2018 ELSEVIER Interaction and inhibitory influence of the azo dye carmoisine on lysozyme amyloid fibrillogenesis. Mol. BioSyst. 13, 1552-1564. 2017 RSC Binding and inhibitory effect of dyes amaranth and tartrazine on amyloid fibrillation in lysozyme. J. Phys. Chem. B 121, 1222–1239. 2017 ACS Binding of the putative anticancer agent chelerythrine to double stranded poly(A): Calorimetry and spectral characterization studies. J. Chem. Thermodyn. 103, 228-233. 2016 ELSEVIER Multispectroscopic and calorimetric studies on the binding of the food colorant tartrazine with human hemoglobin. J. Hazard. Mater. 318, 468-476. 2016 ELSEVIER Spectroscopic and microcalorimetric studies on the molecular binding of food colorant acid red 27 with deoxyribonucleic acid. J. Mol. Recognit. 29, 363-369. 2016 John Wiley & Sons, Ltd. A biophysical investigation on the binding of proflavine with human hemoglobin: Insights from spectroscopy, thermodynamics and AFM studies. J. Photochem. Photobiol. B 165, 42-50. 2016 ELSEVIER Coralyne induced self-structure in polyadenylic acid: Thermodynamics of the structural reorganization. J. Chem. Thermodyn. 101, 221-226. 2016 ELSEVIER Thermodynamics of the induction of self-structure in polyadenylic acid by proflavine. J. Chem. Thermodyn. 100, 100-105. 2016 ELSEVIER Calorimetric investigation on the interaction of proflavine with human telomeric G-quadruplex DNA. J. Chem. Thermodyn. 98, 208-213. 2016 ELSEVIER A microcalorimetric study on the binding of proflavine with tRNAphe. J. Chem. Thermodyn. 97, 173-178. 2016 ELSEVIER Studies on the interaction of the food colorant tartrazine with double stranded deoxyribonucleic acid. J. Biomol. Struct. Dyn. 35, 935-942. 2016 Taylor & Francis The use of calorimetry in the biophysical characterization of small molecule alkaloids binding to RNA structures. Biochim. Biophys. Acta 1860, 930-944. 2016 ELSEVIER Thermodynamic characterization of proflavine-DNA binding through microcalorimetric studies. J. Chem. Thermodyn. 87, 1-7. 2015 ELSEVIER Binding of carmoisine, a food colorant, with hemoglobin: Spectroscopic and calorimetric studies. Food Res. Int. 72, 54-61. 2015 ELSEVIER Interaction of toxic azo dyes with heme protein: Biophysical insights into the binding aspect of the food additive amaranth with human hemoglobin. J. Hazard. Mater. 289, 204-209. 2015 ELSEVIER Thermodynamics of the interaction of the food additive tartrazine with serum albumins: A microcalorimetric investigation. Food Chem. 175, 137-142. 2015 ELSEVIER Interaction of human hemoglobin with food colorants: a multifaceted biophysical study. J. Biomol. Struct. Dyn. 33 (Supplement 1), 131-132. 2015 Taylor & Francis Targeting proteins with toxic azo dyes: A microcalorimetric characterization of the interaction of the food colorant amaranth with serum proteins. J. Agric. Food Chem. 62, 7955-7962. 2014 ACS Interaction of the dietary pigment curcumin with hemoglobin: Energetics of the complexation. Food Funct. 5, 1949-1955. 2014 RSC Binding of novel 9-O-N-aryl/arylalkyl amino carbonyl methyl berberine analogs to poly(U)-poly(A)•poly(U) triplex and comparison to the duplex poly(A)-poly(U). Mol. Biol. Rep. 41, 5473-5483. 2014 Springer Intercalative interaction of the anticancer drug mitoxantrone with double stranded DNA: A calorimetric characterization of the energetics. J. Chem. Thermodyn. 75, 45-51. 2014 ELSEVIER A microcalorimetric study on the interaction of the toxic food additive carmoisine with serum albumins. J. Hazard. Mater. 273, 200-206. 2014 ELSEVIER Interaction of 9-O-N-aryl/arylalkyl amino carbonyl methyl berberine analogs with single stranded ribonucleotides. J. Photochem. Photobiol. B 134, 64-74. 2014 ELSEVIER Elucidating the energetics of the interaction of non-toxic dietary pigment curcumin with human serum albumin: A calorimetric study. J. Chem. Thermodyn. 70, 176-181. 2014 ELSEVIER Minor groove binding of the food colorant carmoisine to DNA: Spectroscopic and calorimetric characterization studies. J. Agric. Food Chem. 62, 317-326. 2014 ACS Biophysical studies on curcumin-deoxyribonucleic acid interaction: spectroscopic and calorimetric approach. Int. J. Biol. Macromol. 62, 257-264. 2013 ELSEVIER Photophysical and calorimetric studies on the binding of 9-O-substituted analogs of the plant alkaloid berberine to double stranded poly(A). J. Photochem. Photobiol. B 125, 105-114. 2013 ELSEVIER Binding of the 9-O-N-aryl/arylalkyl amino carbonyl methyl substituted berberine analogs to tRNAphe. PLoS ONE 8, e58279. 2013 Public Library of Science DNA binding and cleavage activity of a structurally characterized oxobridged diiron(III) complex. Indian J. Chem. Sec. A 52A, 1576-1583. 2013 CSIR-NISCAIR 9-O-N-aryl/arylalkyl amino carbonyl methyl substituted berberine analogues induce self-structure in polyadenylic acid. RSC Adv. 2, 7714-7723. 2012 RSC Synthesis of novel 9-O-N-aryl/arylalkyl amino carbonyl methyl substituted berberine analogs and evaluation of DNA binding aspects. Bioorg. Med. Chem. 20, 2498-2505. 2012 ELSEVIER Binding of 9-(O-ω-amino) alkyl ether analogs of the plant alkaloid berberine to poly(A): insights into self-structure induction. Med. Chem. Commun. 2, 631-637. 2011 RSC Enhanced DNA binding of 9-ω-amino alkyl ether analogs from the plant alkaloid berberine. DNA Cell Biol. 30, 123-133. 2011 Mary Ann Liebert, Inc. National Publication Other Publication Books Published Title of the Book Published by Year Role Binding of food colorants to functional protein Hemoglobin in Handbook of Food Bioengineering, Edited by A.M. Grumezescu and A.M. Holban, VOLUME 7: Natural and Artificial Flavoring Agents and Food Dyes, pp 133-163. ELSEVIER 2017 First Author

Project Work Ongoing Project Works Project title Worked as Funding Agency Amount in Rs. Duration in years Period Year to Year Status Interaction and inhibitory influence of protoberberine alkaloids on amyloid fibrillation in lysozyme Principal Investigator Dept. of Science & Technology and Biotechnology, Govt. of West Bengal 997800 3 year 2019 2022 Ongoing

Invited Lectures  Title Organized by Venue Year Inhibitory effect of ionic liquid 1-Butyl-3-methylimidazolium bromide on amyloid fibrillation in lysozyme 26th FAOBMB Conference and ConBio 2017 held at Kobe, Japan Kobe, Japan 2017

Membership of Learned Society  DNA SOCIETY OF INDIA INDIAN PHOTOBIOLOGY SOCIETY SOCIETY OF BIOLOGICAL CHEMISTS, INDIA

Conference /Seminar/Workshop Attended/Organised Conference /Seminar/Workshop Attended Title of the Seminar/Conference/Workshop Year Role Held at and Organiser Albany 2019: The 20th Conversation 2019 Speaker under Young Scientists Programme Albany, State University of New York, USA 26th FAOBMB Conference and ConBio 2017 2017 Oral Presentation Kobe, Japan from 6-9 December, 2017 International Symposium on Chemical Biology and Drug Design 2016 Paper Presenter March 1st-3rd, 2016, Taj Bengal, Kolkata, India. Albany 2015: The 19th Conversation 2015 Paper Presenter June 9th-13th, 2015, Albany, State University of New York, USA. Asian Conference on Environmental Mutagens 2014 Paper Presenter December 10th-12th, 2014, CSIR-IICB, Kolkata, India. International Symposium on Challenges in Chemical Biology 2013 Paper Presenter January 27th-29th, 2013, Kolkata, India. National Conference on Photosciences: Contemporary Challenges and Future Perspectives 2013 Paper Presenter Jadavpur University, December 12th-14th, 2013, Kolkata, India. National Seminar on Recent Advances in Chemistry 2012 Paper Presenter February 10th-11th, 2012, Jadavpur University, Kolkata, India. Annual Meeting of the Indian Biophysical Society (IBS) 2012 Paper Presenter January 19th-21st, 2012, University of Madras, Maraimalai (Guindy) Campus, Chennai, India. National Symposium on Recent Trends in Biophysics 2011 Paper Presenter February 13th-15th, 2010, Banaras Hindu University, Varanasi, India. International Symposium on Chemistry and Complexity 2011 Paper Presenter December 6th-8th, 2011, Kolkata, India 7th Asian Biophysics Association (ABA) Symposium & Annual Meeting of the Indian Biophysical Society (IBS) 2011 Paper Presenter 29th January-2nd February, 2011, Delhi, India. Conference /Seminar/Workshop Organised

Awards Award Name Awarded By Year International Travel Support SERB 2019 FAOBMB Young Scientist Travel Fellowship Award FAOBMB 2017 SERB National Post Doctoral Fellowship SERB 2016 International Travel Support SERB 2015

Disclaimer : The information on this website has been prepared with the greatest possible care and the aim is to keep all information up-to-date. The University cannot gurantee the correctness, completeness, topicality or quality of the information presented. In the event of doubt concerning the content of the website, please contact the relevant faculty.