VIDYASAGAR UNIVERSITY
Faculty Information System
Self Declared Document


Name Dr. Sagar Acharya
Designation Assistant Professor
Department Name ZOOLOGY
Office Phone No 03222-276554 Extn. 427
Email ID sacharya@mail.vidyasagar.ac.in
Fax 03222-275329
Mobile No 9830427756
Personal Website
Address Department of Zoology, Vidyasagar University, Midnapore, West Bengal, India. Pin-721 102
Educational Qualification
Degree NameInstituteYear of passing/awarded
PhDUniversity of Calcutta, Place of Work: IPGME&R, Kolkata and Calcutta School of Tropical Medicine 2010
M.Sc.University of Calcutta2003
B.Sc.University of Calcutta2001


Career Profile / Teaching Experience
Assistant Professor at Vidyasagar University since 18th April 2012-till date
Guest Lecturer at Postgraduate Dept. of Zoology of Maulana Azad College, Kolkata since 2009-2012
ICMR Centenary Postdoctoral Fellow at National Institute of Cholera & Enteric Diseases (NICED) since 2010-17th April 2012
Senior Research Fellow (CSIR-NET) at Calcutta School of Tropical Medicine, Kolkata since 2008-2010
Senior Research Fellow (CSIR-NET) at IPGME &R, Kolkata since 2007-2008
Junior Research Fellow (CSIR-NET) at IPGME &R, Kolkata since 2005-2007
Research Fellow at IPGME &R, Kolkata since 2004-2005

Specialization/Research Area
Field of SpecializationResearch Area/ Areas of Interest
Genetics
Molecular Biology
Immunology
Cancer
Inflammation
Signal Transduction

Course/ Subject Taught
Cell Biology
Biochemistry
Human genetics
Bio-Statistics
Genetics and Molecular Biology (Special Paper)

Conference/ Symposium /Journal Paper / Books Published
International Publication
TitlePublished inYearPublished by
T11TS inhibits glioma angiogenesis by modulation of MMPs, TIMPs, with related integrin av and TGF-ß1 expressionsTumor Biology 35 (3), 2231-22462014Springer
T11TS impedes glioma angiogenesis by inhibiting VEGF signaling and pro-survival PI3K/Akt/eNOS pathway with concomitant upregulation of PTEN in brain endothelial cellsJournal of neuro-oncology 113 (1), 13-252013Springer
Significant modulation of macrophages associated cytokines TNF-a, VEGF and apoptotoic protein Bax, Bcl2 abrogates tumor cellsCellular immunology 284 (1), 172-1812013Elsevier
T11TS Induced Modulation of Macrophages Associated Cytokines TNF- a,VEGF and Apoptototic Protein Bax, Bcl2 Abrogates Tumor Cells in In vitro Grade I,II Human GliomaJ Clin Cell Immunology 2-9; S1: 006. doi:10.4172/2155-9899.S1-0062013JCCI, an open access journal
Immunomodulatory role of TIITS in respect to cytotoxic lymphocytes in four grades of human glioma.Cellular Immunology 276: 176–186.2012Elsevier
Comparative evaluation of T11 target structure and its deglycosylated derivative nullifies the importance of glycan moieties in immunotherapeutic efficacy.Acta Biochim Biophys Sin (Shanghai) 44(3):259-68.2012ABBS & Institute of Biochemistry and Cell Biology (SIBS, CAS).
Therapeutic Profile of T11TS vs. T11TS+MiADMSA: A Hunt for a More Effective Therapeutic Regimen for Arsenic ExposureAsian Pacific J Cancer Prev, 13, 2943-29482012Asian Pacific Organization for Cancer Prevention and The UICC-Asian Regional Office and An Official Journal of The International Association of Cancer Registries
Chitin-binding protein GbpA of Vibrio cholerae induces interleukin-8 gene expression in intestinal cells through a TLR2/TLR1/CD14 complexThe FASEB Journal 26, 1156.52012FASEB
T11TS exerts effector function by activating immune cells in CNS against glioma where cytokine modulation provide the favourable microenvironment to act.Ind J Exp Biol 48: 879-888.2010NISCAIR
Arsenic induced carcinogenesis: an immunological approach.Asian Pacific Journal of Cancer Prevention 11(2): 479-90.2010Asian Pacific Organization for Cancer Prevention and The UICC-Asian Regional Office and An Official Journal of The International Association of Cancer Registries
Induction of G1 arrest in glioma cells by T11TS is associated with up-regulation of Cip1/Kip1 and concurrent downregulation of cyclin D (1&3).Anti Cancer Drugs; 21: 53–64.2010Wolters Kluwer and Lippincott Williams & Wilkins
Bax and Bid act in synergy to bring about T11TS mediated glioma apoptosis via the release of mitochondrial Cytochrome c and subsequent caspase activation.International Immunology; 2 (12): 1489–1505.2008Oxford University Press & Japanese Society for Immunology
Acute toxicity studies of T11TS: a glycopeptide with antineoplastic effects against glioma.Toxicology International; 14(1) 47-56.2007The Society of Toxicology
The Other Side of the Coin: Beneficiary Effect of ‘Oxidative Burst’ Upsurge with T11TS Facilitates the Elimination of Glioma CellsCellular and Molecular Biology 53(5), 53-62.2007Published by C.M.B. Association,FRANCE
T11TS/SLFA-3 Differentially Regulate The Population Of Microglia And Brain Infiltrating Lymphocytes To Reduce Glioma By Modulating Intrinsic Bcl-2 Expression Rather Than p53.Central Nervous System Agents in Medicinal Chemistry. 7, 145-155.2007Bentham Science Publishers
A sequential scanning of the immune efficiency in Astrocytoma (Grade I-Grade III), Meningioma & Secondary glioma patients with and without therapeutic schedulingCancer Investigation, 24(5):502-5132006Informa Healthcare London, UK


National Publication
TitlePublished inYearPublished by
Subacute toxicity study of T11TS: A Nove immunotherapeutic glycopeptide against glioma.Advances in Pharmacology & Toxicology. 11 (1): 1-10.2010Connect-Journals (CJ)
Differential functional modulation of the death proteins in in vivo and in vitro microenvironments in experimental brain tumors (glioma)Journal of Cell & Tissue Research; 8(1):1211-1224.2008CTR Publications
A Novel Adjuvant Immunotherapeutic Approach In Treating Canine PyodermaAdv. Life Sc. 1(1): 9-19.2008IJALS
Functional and receptor modulations of T lymphocytes and macrophage in acute and subacute dose finding studies of a novel immunotherapeutic molecule T11TS.Journal of Cell & Tissue Research 7(2):1013-1018.2007CTR Publications


Other Publication


Books Published

Project Work

Ongoing Project Works
Project titleWorked asFunding AgencyAmount in Rs.Duration in yearsPeriod
Year to Year
Status
Delineating signal cascades induced by colonization factor of Enterotoxigenic E. coliPrincipal InvestigatorUGC6000002 year20142016



Conference /Seminar/Workshop Attended/Organised

Conference /Seminar/Workshop Attended

Title of the Seminar/Conference/WorkshopYearRoleHeld at and Organiser
Continuing Medical Education (CME) cum Workshop on Stem Cell Therapy and Research2011AttendedNetaji Subhas Chandra Bose Cancer Research Institute, Kolkata.
National Conference on Interface of Science & Environment: Emerging Public Health Challenges, SCIENVIRON2011Attended13th Annual Meeting of Society of Science & Environment. Kolkata
5th World Congress of Cellular and Molecular Biology organized by World Society Cellular and Molecular Biology, France2009Paper PresenterWorld Society Cellular and Molecular Biology, France in collaboration with Dept. of Biotechnology. Devi Ahilya University, Indore
International conference on Integrative Physiology: Modern Perspective2009Paper PresenterPhysilogical Society of India, Kolkata
New frontiers in Scientific Meet on Heamatology and oncology2009AttendedNetaji Subhas Chandra Bose Cancer Research Institute, Kolkata
Workshop on “Bioinformatics in Genomics & Proteomics2008AttendedIIT, Kharagpur
Indian Academy of Neurosciences, Kolkata Chapter2007Paper PresenterS.N.Pradhan Centre foe Neurosciences, University of Calcutta
34th Annual Conference of the Indian Immunology Society2007Poster PresentationIndian Immunology Society, National AIDS Research Institute, Pune
New frontiers in Scientific Meet on Heamatology and oncology2007Paper PresenterNetaji Subhas Chandra Bose Cancer Research Institute, Kolkata
National Seminar on Dimension in Zoological Research in Human Welfare2007Paper PresenterDepartment of Zoology, University of Calcutta & The Zoological Society, Kolkata
The XVIII Annual Conference of The Physiological Society of India2006Paper PresenterDepartment of Physiology, Presidency College, Kolkata
Brain Tumors - WFNS - World Federation of Neurosurgical Societies, Kolkata chapter2006AttendedNational Neuroscience Centre, Kolkata


Conference /Seminar/Workshop Organised


Awards
Award NameAwarded ByYear
ICMR Centenary Postdoctoral FellowshipIndian Council of Medical Research, Govt. of India2010
CSIR-NET-JRF in LIFE SCIENCESCSIR-UGC, Govt. of India2004
NET - Lectureship in Life SciencesCSIR-UGC, Govt. of India2004
NET - Lectureship in Life SciencesCSIR-UGC, Govt. of India2003
National Scholarship SchemeGovt. of India2001

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